Optimizing and confirming AAV designs with PacBio sequencing

Tutorial and industry panel discussion

Full-length sequencing data of recombinant adeno-associated virus (rAAV) vectors is critical to the development of effective gene therapy products. Highly accurate HiFi sequencing has the unique advantage of capturing and sequencing entire AAV genomes so gene therapy researchers can characterize potential therapeutic products with confidence and precision.

In this on-demand bioinformatics webinar, PacBio scientist Dr. Elizabeth Tseng demonstrates how to generate and analyze full-length AAV sequencing data to profile packaged genomes as a single intact molecule, measure impurities, and ensure vectors contain the intended design. Watch the recording to also hear industry leaders at Homology Medicines and AavantiBio discuss how, when, and where they use the PacBio full-length AAV sequencing platform to improve their overall gene therapy research program and comprehensively assess their designs.


  • Understand the unique advantages of HiFi reads for AAV sequencing
  • Hear about publication highlights that use HiFi sequencing for AAV research
  • Learn about the latest software developments for interpreting PacBio AAV sequencing data – no bioinformatics experience necessary
  • Watch a panel discussion with two industry guests discussing their use of PacBio technology for their AAV therapy research programs 

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Speakers and Panelists

Elizabeth Tseng, PhD
Associate Director of Product Marketing
John F. Thompson, PhD
VP of Genomics and Computational Biology
Homology Medicines
Guest Panelist
Adam Cockrell, PhD
Senior Director of Vector Biology
Guest Panelist

Democratizing Genome Assembly and Annotation

Ted Kalbfleisch, Ph.D., Associate Professor, University of Kentucky

Molecular Genetic Applications Enabled by Platinum Quality Reference Genome Assemblies in Octoploid Strawberry

Mitchell Feldmann, Ph.D., Postdoctoral Fellow, University of California, Davis.