MEASURING DNA METHYLATION WITH 5-BASE HIFI SEQUENCING
PacBio’s latest update extends our unique and standard-setting HiFi sequencing to include access to the epigenome through automatic detection of 5mC bases in native DNA. Using standard sample preparation workflows and requiring no additional sequencing, equipment, or associated costs, this capability unlocks new research possibilities across a broad range of applications.
In this application brief, you'll learn about:
How HiFi sequencing simultaneously measures the genome and epigenome