ESHG 2022

Sequence without compromise

  11-14 June 2022

Meet the PacBio team at the ESHG conference in Vienna to learn how PacBio sequencing enables researchers to see more and do more.

At PacBio we create the world’s most advanced sequencing systems to provide researchers the most complete and accurate view of genomes, transcriptomes, and epigenomes. 

Highly accurate long-read sequencing, known as HiFi sequencing, provides a higher resolution approach compared to previously used technologies to better understand the genetic causes of rare disease.

Below you’ll discover the many ways to engage with us at the conference. We look forward to meeting you.

 

Highlights of the event include:

  • Corporate Satellite 
  • In-booth presentations
  • Meet our sequencing experts

Not able to attend ESHG 2022? Then make sure to fill out the form to receive copies of our posters, and other materials we'll present at the conference.


Register to receive copies of our content presented at ESHG


By registering on this web page, you are consenting and agreeing to collection and use of that information by PacBio in accordance with its privacy policy.

Corporate Satellite

PacBio sequencing: See what you’ve been missing

Sunday, June 12, 2022 14:15–15:45
Room Room M 1+2, Level 1
  

Speakers

PacBio sequencing and its applications

Neil Ward, GM and Vice President EMEA, PacBio

Closing the gap: Solving complex medically relevant dark regions of the human genome

Fritz Sedlazeck, Dr. rer. nat. and Associate Professor, Baylor College of Medicine, Houston, USA

Accurate long reads for rare disease research

Alexander Hoischen, PhD and Associate Professor, Radboudumc, Nijmegen, The Netherlands

Single-cell analysis of alternative splicing in hematopoietic stem and progenitor Cells

Laura Mincarelli, PhD, Beatson Institute for Cancer Research, UK

Michael Eberle, PhD, VP Computational Biology, PacBio

Detecting the full spectrum of genomic variation with HiFi long reads

Michael Eberle, PhD, VP Computational Biology, PacBio

TBP

TBP

Pacbio Poster Presentations

Scalable PacBio HiFi Library Prep for High-Quality Genome Assemblies

Authors: Jacob Brandenburg, Aaron Wenger, Christine Lambert, Heather Ferrao  

Jacob Brandenburg, Senior Specialist, Segment Marketing, PacBio

Long-read whole genome sequencing (WGS) for plants and animals has allowed scientists to tackle the assembly of genomes ranging in size, ploidy, and repeat content. HiFi WGS enables complete, accurate, and contiguous assemblies of even the most complex genomes. As a result, HiFi WGS has been adopted by many biodiversity genomics consortia and agriculture researchers to assemble thousands of genomes. While HiFi WGS simplifies the bioinformatics of genome assembly, library preparation remains a common challenge, especially for scientists sequencing organisms which yield low quantities of DNA or have very large genomes that require multiple libraries for a single de novo assembly. We describe a new workflow using the PacBio SMRTbell Prep Kit 3.0 that is amenable to automation while significantly reducing the time (by 50%), cost, and DNA quantity (by 40%) necessary to prepare a sequencing library. We applied the workflow to rice and fly samples and demonstrate that the assembly quality matches that of the previous, more time-consuming library prep workflows. This new workflow offers a more efficient solution for all WGS applications, regardless of organism size or complexity. 

An Evaluation of Bioinformatics Tools for HiFi Plant Pangenomes

Authors: Greg Concepcion, Michelle Vierra 

Greg Concepcion, Staff Engineer, Bioinformatics, PacBio

With the increasing prevalence of high-quality assembled genomes, access to the pangenomes of species is now an achievable possibility for researchers with all research budgets. However, the tools to visualize, analyze, and extract actionable information from these pangenome datasets are still in their infancy. Using a large plant pangenome dataset, we evaluated the pangenome graph builder  pipeline for building a pangenome graph of the species and use these evaluations to provide basic recommendations for how to best manipulate and visualize these pangenomic datasets with other downstream tools including the vg toolkit.

Pacbio Presentations

Monday, October XX X:00 pm PST

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Presenter name, title, credentials, Presenter name, title, credentials

Presenter name, title, credentials, Presenter name, title, credentials

Pacbio colab talk

Monday, October XX X:00 pm PST

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Presenter name, title, credentials, Presenter name, title, credentials

Presenter name, title, credentials, Presenter name, title, credentials

Presentations + Posters

# Title Presenter Date
P16.009.A Closing the gap: Solving complex medically relevant regions of the human genome F. Sedlazeck 12/06/2022, 13:00-14:00
P16.026.B Enablement of long-read targeted sequencing panels using Twist hybrid capture and PacBio HiFi sequencing G. Henno 12/06/2022, 16:00-17:00
P16.018.B Integrated heteroduplex correction in PacBio’s circular consensus algorithm Z. Kronenberg 12/06/2022, 16:00-17:00
P16.015.C Genome-wide CpG methylation calling with standard HiFi whole genome sequencing J. Blethrow 13/06/2022, 12:45-13:45
P19.024.C Typing CYP2D6 star alleles from fully phased variants using PacBio HiFi reads N. Gonzaludo 13/06/2022, 12:45-13:45
Presenter Title Date/Time
Dr Mike Eberle
PacBio
Latest bio-informatics tools for HiFi data 6/11/2022 @ 10:00
6/12/2022 @ 15:45
Dr Nina Gonzaludo
PacBio
PGx analysis without compromise 6/11/2022 @ 16:00
6/13/2022 @ 10:00
Dr Jorge Pinto Basto
Senior Medical Director
CENTOGENE GmbH
Performance of HiFi WGS on dry blood spot samples, a proof of concept 6/12/2022 @ 10:00
6/13/2022 @ 15:30

Visit us at booth #X5-364

Stop by our booth to chat with PacBio staff and have your questions answered.

We are excited to learn about your sequencing goals and learn more about your research.

Booth hours:

  • Sunday 9 June: 9:30–18:30 
  • Monday 10 June: 9:30–17:15 
  • Tuesday 11 June: 9:30–17:15

PacBio Service Providers

Interested in getting a sequencing project started? Stop by our service providers at PAG to talk about project design and next steps.

Booth 211

Booth 406

Booth 503

Booth 523

Booth 319

Booth 434

Get in touch

Speak to a sequencing specialist
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