Pacific Biosciences Workshop:
Whole Human Genome SMRT® Sequencing Reveals Uncharacterized Structural Variations Providing a Path to More Informed Diagnostic Testing

Eric Schadt, Ph.D.
Director, Icahn Institute for Genomics and Multiscale Biology at Mount Sinai School of Medicine

Friday, February 22, 3:20 p.m. – 3:40 p.m.
Islands Ballroom

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Thursday, February 21

Deep Sequencing of Immune Repertoires During Bovine Development and in Response to Respiratory Pathogen Challenge
- Tim Smith, Ph.D., U.S. Meat Animal Research Center

8:30 p.m. – 8:50 p.m., Islands Ballroom

Spatiotemporal Dynamics of the Epitranscriptome Reveal Novel Mechanisms of RNA Regulation
- Christopher Mason, Ph.D., Cornell Medical College

8:30 p.m. – 8:50 p.m., Salon G through J

Friday, February 22

Assembling Crop Genomes with Single Molecule Sequencing
- Michael Schatz, Ph.D., Cold Spring Harbor Laboratory

9:10 p.m. – 9:30 p.m., Salon G through J

Saturday, February 23

Increased Read Length and Sequence Quality with Pacific Biosciences MagBead Loading System and a New DNA Polymerase
- Eric Antoniou, Ph.D., Cold Spring Harbor Laboratory

9:30 a.m. – 9:55 a.m., Islands Ballroom

Automated, Non-Hybrid De Novo Genome Assemblies and Epigenomes of Bacterial Pathogens
- Jonas Korlach, Ph.D., Pacific Biosciences

11:35 a.m. – 12:00 p.m., Islands Ballroom

Thursday, February 21, 1:00 p.m. - 2:30 p.m.

#74: Optimization of Procedures of Genomic DNA Preparation in Diverse Organisms for Single Molecule, Real-Time Sequencing
 - Tomoko Shibata et al., National Institute of Basic Biology

#80: Integration of NGS Desktop Sequencers to Build a Global Genomic Network for Pathogen Trace-back and Outbreak Detection: Error Rates are not the Sole Criteria for Determining Applications for Instrumentation
 - Marc Allard et al., U.S. Food & Drug Administration

#99: Application of SMRT® Genome Sequencing to Reveal the Methylomes of Bacteria Associated with Respiratory Disease Outbreaks in Beef Cattle
 - Gregory Harhay et al., USDA-ARS-USMARC

#114: Closing Gaps in Finished Genomes using Long Reads and Local BAC Assembly
 - Todd Michael, Monsanto Company

#185: Advances in Sequence Consensus and Clustering Algorithm for Effective De Novo Assembly and Haplotyping Applications with SMRT® Sequencing
 - Jason Chin et al., Pacific Biosciences

#201: Assembling PacBio® Continuous Long Reads without Using Other Types of Reads
 - Takamasa Imai et al., The University of Tokyo

#210: Fast and Scalable Error Correction of SMRT Sequencing Human Genome Reads with Illumina Reads
 - Shoichiro Oishi et al., University of Tokyo

#260: Direct Sequencing of Small Genomes on the PacBio RS without Library Preparation
 - Paul Coupland et al., Wellcome Trust Sanger Institute

#277: Evaluating Genome Sequencing and Assembly Strategies for Diverse Microbial Pathogens
 - Xinyue Liu et al., University of Maryland, Institute for Genome Sciences

#300: Towards Rapid and Cost-effective Whole Exome Sequencing for Clinical Diagnosis and Personalized Medicine
 - Mark Wang, Baylor College of Medicine

#333: Full Length cDNA Sequencing on the PacBio® RS
 - Jason Underwood et al., Pacific Biosciences

Join us for some California-style beach volleyball!
Gatorade and snacks provided.

When: 7 a.m. on Thursday, Friday, and possibly Saturday (weather permitting)
Where: At the sand courts outside the Marriott Hotel

Or feel free to come cheer us on!!!

Program Presentations

Posters

Friday, February 22, 4:30 p.m.– 6:00 p.m

#41: Single Molecule, Real-Time Sequencing for Base Modification Detection in Eukaryotic Organisms

 - Khai Luong et al., Pacific Biosciences

#51: Estimating Unmethylated DNA Blocks in Vertebrates by SMRT Sequencing
 - Yuta Suzuki et al., The University of Tokyo

#73: Phasing Variants in Poplar Trees using a Hybrid of Short and Long Read Technologies
 - Wendy Schackwitz et al., Lawrence Berkeley National Lab - JGI

#94: The Use of Long Sequence Reads to Ameliorate Microbial Genome Assemblies
 - Ken Dewar et al., McGill Universtiy

#96: The ABRF-NGS: a Five Platform, Cross-Site, Cross-Protocol Examination of RNA Sequencing
 - George Grills, Cornell University

#100: Pacific Biosystems SMRT® Technology as a Confirmatory Methodology for the Verification of DNA Sequence Variants found by NGS
 - Ed Highsmith, Jr. et al., Mayo Clinic

#117: SMRT® Sequencing for High-Resolution Typing and Phasing of HLA Alleles
 - Swati Ranade et al., Pacific Biosciences

#140: Human MUC5AC Genome Sequence:  Filling the Reference Gap by De Novo Assembly of PacBio Long Sequencing Reads
 - Hong Dang et al., UNC-Chapel Hill

#209: De Novo Assembly of Genomes Using Large Insert Pacific Biosciences® SMRT Sequencing Reads
 - Joel Martin et al., Lawrence Berkeley National Lab - JGI

#291: Characterizing and Measuring Bias in Sequence Data
 - Michael Ross et al., Broad Institute of MIT and Harvard

For Research Use Only. Not for use in diagnostic procedures. © Copyright 2013, Pacific Biosciences of California, Inc. All rights reserved. Information in this document is subject to change without notice. Pacific Biosciences assumes no responsibility for any errors or omissions in this document. Certain notices, terms, conditions and/or use restrictions may pertain to your use of Pacific Biosciences products and/or third party products. Please refer to the applicable Pacific Biosciences Terms and Conditions of Sale and to the applicable license terms at http://www.pacificbiosciences.com/licenses.html.
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Program Presentations
Posters
Other Activities

Early Riser?
Evening Party

Join us for an evening of cocktails, hors d'oeuvres, and great conversation.

When: Friday, February 22, 9:30 p.m. - Midnight
Where: Lanai Suite #193


We look forward to hosting you!